Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant Promoter Methylation Profile and Association with Survival in Patients with Non–Small Cell Lung Cancer

15 Dec 2006

Abstract excerpt

PURPOSE: The aim of this study was to investigate the prognostic value of hypermethylation of tumor suppressor genes in patients with non-small cell lung cancer (NSCLC). EXPERIMENTAL DESIGN: We examined the methylation status of nine genes in 155 tumors from patients with NSCLC using quantitative methylation-specific PCR. We analyzed the associations between gene methylation status and overall patient survival....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17189404
DOI: 10.1158/1078-0432.ccr-06-0894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant Promoter Methylation Profile and Association with Survival in Patients with Non–Small Cell Lung CancerPMID 17189404Read ↗

Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis.Semantic proximity Read ↗

The role of DNA methylation and DNA methyltransferases (DNMTs) as potential biomarker and therapeutic target in non-small cell lung cancer (NSCLC)Semantic proximity Read ↗

Prognostic significance of CpG island methylator phenotype in surgically resected small cell lung carcinoma.Semantic proximity Read ↗

DNA methylation and nonsmall cell lung cancer.Semantic proximity Read ↗

Genomewide DNA methylation analysis identifies novel methylated genes in non-small-cell lung carcinomas.Semantic proximity Read ↗

Promoter methylations of RASSF1A and p16 is associated with clinicopathological features in lung cancers.Semantic proximity Read ↗

DNA methylation: its role in lung carcinogenesis and therapeutic implications.Semantic proximity Read ↗

Elevated mRNA levels of DNA methyltransferase‐1 as an independent prognostic factor in primary nonsmall cell lung cancerSemantic proximity Read ↗

Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk factors.Semantic proximity Read ↗

Quantitative assessment of lung cancer associated with genes methylation in the peripheral blood.Semantic proximity Read ↗

Association of RASSF1A promoter methylation with lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Epigenetic effects of lung cancer predisposing factors impact on clinical diagnosis and prognosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.