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Article

Apolipoprotein L1 High-Risk Genotypes and Albuminuria in Sub-Saharan African Populations.

Clinical journal of the American Society of Nephrology : CJASN - 1 Jun 2022

Brandenburg Jean-Tristan, Govender Melanie A, Winkler Cheryl A, Boua Palwende Romuald, Agongo Godfred, Fabian June, Ramsay Michèle

Abstract excerpt

BACKGROUND AND OBJECTIVES: Recessive inheritance of African-specific APOL1 kidney risk variants is associated with higher risk of nondiabetic kidney disease, progression to kidney failure, and early-onset albuminuria that precedes eGFR decline. The effect of APOL1 risk variants on kidney disease in continental Africans is understudied. Objectives of this study were to determine APOL1 risk allele prevalence and...

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Identifiers

PMID: 35577564
DOI: 10.2215/CJN.14321121
PMCID: PMC9269651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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