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Article

Genetic risk of APOL1 and kidney disease in children and young adults of African ancestry.

Current opinion in pediatrics - 1 Apr 2018

Reidy Kimberly J, Hjorten Rebecca, Parekh Rulan S

Abstract excerpt

PURPOSE OF REVIEW: Understanding the genetic risk of APOL1 in children and young adults is important given the lifetime risk of hypertension and kidney disease among children of African descent. We review recent epidemiologic and biologic findings on the effects of APOL1 and kidney disease. RECENT FINDINGS: APOL1 in children and young adults is associated with hypertension, albuminuria and more rapid decline in...

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Source

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Identifiers

PMID: 29406442
DOI: 10.1097/MOP.0000000000000603
PMCID: PMC6002812

Genes

APOL1

Provenance

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