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Article

Multiple pathway-based genetic variations associated with tobacco related multiple primary neoplasms.

PloS one - 1 Jan 2012

Kotnis Ashwin, Namkung Junghyun, Kannan Sadhana, Jayakrupakar Nallala, Park Taesung, Sarin Rajiv, Mulherkar Rita

Abstract excerpt

BACKGROUND: In order to elucidate a combination of genetic alterations that drive tobacco carcinogenesis we have explored a unique model system and analytical method for an unbiased qualitative and quantitative assessment of gene-gene and gene-environment interactions. The objective of this case control study was to assess genetic predisposition in a biologically enriched clinical model system of tobacco related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22253860
DOI: 10.1371/journal.pone.0030013
PMCID: PMC3256192

Genes

XRCC1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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