Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic, genetic and environmental interactions in esophageal squamous cell carcinoma from northeast India.

PloS one - 1 Jan 2013

Talukdar Fazlur Rahman, Ghosh Sankar Kumar, Laskar Ruhina Shirin, Mondal Rosy

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) develops as a result of complex epigenetic, genetic and environmental interactions. Epigenetic changes like, promoter hypermethylation of multiple tumour suppressor genes are frequent events in cancer, and certain habit-related carcinogens are thought to be capable of inducing aberrant methylation. However, the effects of environmental carcinogens depend upon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

Share to Gene-Environment Interaction

Share to Glutathione Transferase

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 23596512
DOI: 10.1371/journal.pone.0060996
PMCID: PMC3626640

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic, genetic and environmental interactions in esophageal squamous cell carcinoma from northeast India.PMID 23596512Read ↗

Gene-environment interaction and susceptibility in head and neck cancer patients and in their first-degree relatives: a study of Northeast Indian population.Semantic proximity Read ↗

Interactions between Glutathione-S-Transferase M1, T1 and P1 polymorphisms and smoking, and increased susceptibility to esophageal squamous cell carcinoma.Semantic proximity Read ↗

Tobacco carcinogen-metabolizing genes CYP1A1, GSTM1, and GSTT1 polymorphisms and their interaction with tobacco exposure influence the risk of head and neck cancer in Northeast Indian population.Semantic proximity Read ↗

Genotypes of CYP1A1, SULT1A1 and SULT1A2 and risk of squamous cell carcinoma of esophagus: outcome of a case-control study from Kashmir, India.Semantic proximity Read ↗

Interaction of glutathione-s-transferase genotypes with environmental risk factors in determining susceptibility to head and neck cancer and treatment response and survival outcome.Semantic proximity Read ↗

GSTT1, GSTM1 and GSTP1 genetic polymorphisms and interaction with tobacco, alcohol and occupational exposure in esophageal cancer patients from North IndiaSemantic proximity Read ↗

Association of xenobiotic metabolizing enzymes genetic polymorphisms with esophageal cancer in Kashmir Valley and influence of environmental factors.Semantic proximity Read ↗

Risk modulation of GSTM1–GSTT1 interactions to head and neck cancer in tobacco users.Semantic proximity Read ↗

p16 hypermethylation: a biomarker for increased esophageal cancer susceptibility in high incidence region of North East India.Semantic proximity Read ↗

Gene-environment interactions associated with CYP1A1 MspI and GST polymorphisms and the risk of upper aerodigestive tract cancers in an Indian population.Semantic proximity Read ↗

Genetic susceptibility and environmental factors of esophageal cancer in Xi'an.Semantic proximity Read ↗

Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard to the consumption of alcohol, tobacco and betel quid.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.