Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of platelet-derived growth factor-A expression in mouse tissues using a lacZ knock-in approach.

PloS one - 1 Jan 2014

Andrae Johanna, Gouveia Leonor, He Liqun, Betsholtz Christer

Abstract excerpt

Expression of the platelet-derived growth factor A-chain gene (Pdgfa) occurs widely in the developing mouse, where it is mainly localized to various epithelial and neuronal structures. Until now, in situ mRNA hybridization (ISH) has been the only reliable method to identify Pdgfa expression in tissue sections or whole mount preparations. Validated protocols for in situ detection of PDGF-A protein by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Expression
Share to Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Platelet-Derived Growth Factor

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 25166724
DOI: 10.1371/journal.pone.0105477
PMCID: PMC4148317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of platelet-derived growth factor-A expression in mouse tissues using a lacZ knock-in approach.PMID 25166724Read ↗

A Pdgf-cCreERT2 knock-in mouse model for tracing PDGF-C cell lineages during development.Semantic proximity Read ↗

Generation of conditional knockout alleles for PDGF-C.Semantic proximity Read ↗

Insight into the physiological functions of PDGF through genetic studies in mice.Semantic proximity Read ↗

Generation of an EphA4 conditional allele in mice.Semantic proximity Read ↗

A human YAC transgene rescues craniofacial and neural tube development inPDGFRα knockout mice and uncovers a role for PDGFRα in prenatal lung growthSemantic proximity Read ↗

Platelet-Derived Growth Factor C Deficiency in C57BL/6 Mice Leads to Abnormal Cerebral Vascularization, Loss of Neuroependymal Integrity, and Ventricular AbnormalitiesSemantic proximity Read ↗

Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line.Semantic proximity Read ↗

Dandy Walker-like malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar developmentSemantic proximity Read ↗

Temporally and spatially controlled expression of transgenes in embryonic and adult tissues.Semantic proximity Read ↗

Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure.Semantic proximity Read ↗

PDGF function in diverse neural crest cell populations.Semantic proximity Read ↗

Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.