Article
Generation of an EphA4 conditional allele in mice.
Genesis (New York, N.Y. : 2000) - 1 Feb 2010
Herrmann Julia E, Pence Morgan A, Shapera Emanuel A, Shah Ravi R, Geoffroy Cédric G, Zheng Binhai
Abstract excerpt
Ephrins and Eph receptor tyrosine kinases are cell-surface molecules that serve a multitude of functions in cell-cell communication in development, physiology, and disease. EphA4 is a promiscuous member of the EphA subclass of Eph receptors and can bind to both EphrinAs and EphrinBs. In addition to its well-established roles in guiding the development of neuronal connectivity, EphA4 has been implicated for a role...
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