Article
Generation of conditional knockout alleles for PDGF-C.
Genesis (New York, N.Y. : 2000) - 1 Oct 2007
Wu Xiaoli, Ding Hao
Abstract excerpt
PDGF-C is a newly identified member of the platelet-derived growth factor (PDGF) family, which is involved in multiple cellular functions by signaling through PDGF receptor (PDGFR)-alphaalpha and alphabeta dimers. PDGF-C deficiency is perinatal lethal due to the formation of cleft palate. To further characterize the cellular function of PDGF-C during both embryonic and postnatal development, we have generated two...
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