Article
Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line.
Cell biochemistry and biophysics - 1 Sept 2021
Rivera Richard, Williams Nyssa A, Kennedy Grace G, Sánchez-Pavón Paloma, Chun Jerold
Abstract excerpt
Lysophosphatidic acid (LPA) is a lysophospholipid that acts as an extracellular signal through the activation of cognate G protein-coupled receptors (GPCRs). There are six known LPA receptors (LPA1-6). The first such receptor, LPA1, was identified in the embryonic brain and has been studied extensively for gene expression throughout the body, including through studies of receptor-null mice. However, identifying...
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