Article
Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] - 1 Jan 2015
Reuther Sebastian, Szymczak Silke, Raabe Annette, Borgmann Kerstin, Ziegler Andreas, Petersen Cordula, Dikomey Ekkehard, Hoeller Ulrike
Abstract excerpt
BACKGROUND AND PURPOSE: The aim of this study was to determine the impact of functional single nucleotide polymorphism (SNP) pathways involved in the ROS pathway, DNA repair, or TGFB1 signaling on acute or late normal toxicity as well as individual radiosensitivity. MATERIALS AND METHODS: Patients receiving breast-conserving surgery and radiotherapy were examined either for erythema (n = 83), fibrosis (n = 123),...
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