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Article

Polymorphic Variants in Oxidative Stress Genes and Acute Toxicity in Breast Cancer Patients Receiving Radiotherapy.

Cancer research and treatment - 1 Jul 2016

Córdoba Elisa Eugenia, Abba Martín Carlos, Lacunza Ezequiel, Fernánde Eduardo, Güerci Alba Mabel

Abstract excerpt

PURPOSE: Reactive oxygen species (ROS) are generated as an indirect product of radiation therapy (RT). Genetic variation in genes related to ROS metabolism may influence the level of RT-induced adverse effects. We evaluated the potential association of single nucleotide polymorphism (SNP)-related response to radiotherapy injury in breast cancer patients undergoing RT. MATERIALS AND METHODS: Eighty patients...

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Source

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Identifiers

PMID: 26790968
DOI: 10.4143/crt.2015.360
PMCID: PMC4946367

Genes

NOS3
GSTA1
GSTP1
SOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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