Article
SNPs in DNA repair or oxidative stress genes and late subcutaneous fibrosis in patients following single shot partial breast irradiation.
Journal of experimental & clinical cancer research : CR - 24 Jan 2012
Falvo Elisabetta, Strigari Lidia, Citro Gennaro, Giordano Carolina, Boboc Genoveva, Fabretti Fabiana, Bruzzaniti Vicente, Bellesi Luca, Muti Paola, Blandino Giovanni, Pinnarò Paola
Abstract excerpt
BACKGROUND: The aim of this study was to evaluate the potential association between single nucleotide polymorphisms related response to radiotherapy injury, such as genes related to DNA repair or enzymes involved in anti-oxidative activities. The paper aims to identify marker genes able to predict an increased risk of late toxicity studying our group of patients who underwent a Single Shot 3D-CRT PBI (SSPBI)...
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