Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms influencing total and γ' fibrinogen levels and fibrin clot properties in Africans.

British journal of haematology - 1 Jan 2015

Kotzé Retha C, Nienaber-Rousseau Cornelie, De Lange Zelda, De Maat Moniek P, Hoekstra Tiny, Pieters Marlien

Abstract excerpt

Inter-ethnic variation in fibrinogen levels is hypothesized to be the result of differences in genetic background. No information is available regarding the contribution of genetics to fibrinogen γ' in Africans. Only limited information is available regarding the interaction between genotypes and total and γ' fibrinogen concentration in determining fibrin clot properties. Our aim was to investigate the effect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Coagulation

Share to Fibrin

Share to Fibrinogen

Share to Gene-Environment Interaction

Share to Gene Frequency

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 25156046
DOI: 10.1111/bjh.13104

Genes

FGA
FGB
FGG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms influencing total and γ' fibrinogen levels and fibrin clot properties in Africans.PMID 25156046Read ↗

Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations.Semantic proximity Read ↗

Homocysteine influences blood clot properties alone and in combination with total fibrinogen but not with fibrinogen γ' in Africans.Semantic proximity Read ↗

Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction.Semantic proximity Read ↗

The association of alcohol with circulating total fibrinogen and plasma clot density is mediated by fibrinogen and FXIII genotypesSemantic proximity Read ↗

Identification of gene-gene and gene-environment interactions within the fibrinogen gene cluster for fibrinogen levels in three ethnically diverse populations.Semantic proximity Read ↗

Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study.Semantic proximity Read ↗

The contribution of genetic and environmental factors to changes in total and γ' fibrinogen over 5 years.Semantic proximity Read ↗

Candidate gene analysis of the fibrinogen phenotype reveals the importance of polygenic co-regulation.Semantic proximity Read ↗

Fibrinogen as a Pleiotropic Protein Causing Human Diseases: The Mutational Burden of Aα, Bβ, and γ Chains.Semantic proximity Read ↗

Association of Genetic Polymorphisms of Fibrinogen, Factor XIII A-Subunit and α2-Antiplasmin with Fibrinogen Levels in Pregnant WomenSemantic proximity Read ↗

Assessment of genetic determinants of the association of γ' fibrinogen in relation to cardiovascular disease.Semantic proximity Read ↗

Functional and structural consequences of fibrinogen γ-chain variants associated with thrombotic phenotype in congenital fibrinogen disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.