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Article

Genetic epidemiology of pharmacogenetic variations in CYP2C9, CYP4F2 and VKORC1 genes associated with warfarin dosage in the Indian population.

Pharmacogenomics - 1 Jul 2014

Giri Anil K, Khan Nazir M, Grover Sandeep, Kaur Ismeet, Basu Analabha, Tandon Nikhil, Scaria Vinod, Kukreti Ritushree, Brahmachari Samir K, Bharadwaj Dwaipayan

Abstract excerpt

AIM: Warfarin, a widely used anticoagulant, exhibits large interindividual variability in dose requirements. CYP2C9 and VKORC1 polymorphisms in various ethnic groups have been extensively studied as genetic markers associated with variable drug response. However, allele frequencies of these variants have not been assessed in major ethnic groups in the Indian population. MATERIALS & METHODS: To study the...

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Source

Identifiers

PMID: 25155935
DOI: 10.2217/pgs.14.88

Genes

VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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