Article
Combined CYP2C9, VKORC1 and CYP4F2 frequencies among racial and ethnic groups.
Pharmacogenomics - 1 Jun 2010
Scott Stuart A, Khasawneh Rame, Peter Inga, Kornreich Ruth, Desnick Robert J
Abstract excerpt
AIMS: CYP4F2*3 (p.V433M) has been associated with higher warfarin dose requirements; however, its frequency, like other CYP2C9 and VKORC1 variants, has not been systematically assessed in major racial/ethnic populations. Thus, we determined the individual and combined frequencies of important CYP2C9, VKORC1 and CYP4F2 variants in several racial/ethnic groups. MATERIALS & METHODS: Healthy African-American, Asian,...
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