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Article

Worldwide allele frequency distribution of four polymorphisms associated with warfarin dose requirements.

Journal of human genetics - 1 Sept 2010

Ross Kendra A, Bigham Abbigail W, Edwards Melissa, Gozdzik Agnes, Suarez-Kurtz Guilherme, Parra Esteban J

Abstract excerpt

The aim of the study is to improve our understanding of the worldwide allele frequency distribution of four genetic polymorphisms known to influence warfarin dosing (VKORC1 rs9923231, CYP2C9 rs1799853, CYP2C9 rs1057910 and CYP4F2 rs2108622). These four polymorphisms were genotyped in the Human Genome Diversity Project-Centre Etude Polymorphism Humain (HGDP-CEPH) worldwide sample (N=963), as well as in a sample of...

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Source

Identifiers

PMID: 20555338
DOI: 10.1038/jhg.2010.73

Genes

VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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