Article
VKORC1 and CYP2C9 genotype distribution in Asian countries.
Thrombosis research - 1 Sept 2014
Gaikwad Tejasvita, Ghosh Kanjaksha, Shetty Shrimati
Abstract excerpt
BACKGROUND: Warfarin is the most widely used anticoagulant all over the world for prevention and treatment of different thrombotic conditions. Polymorphisms in two genes i.e. CYP2C9 (Cytochrome P450 2C9) and VKORC1 (Vitamin K epoxide reductase complex subunit 1) play a major role in warfarin dose variation and its related adverse effects. Different ethnic groups have shown significant differences in dose...
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