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Development and validation wise assessment of genotype guided warfarin dosing algorithm in Indian population.

Drug metabolism and personalized therapy - 1 Sept 2023

Anand Aishwarya, Kumar Rupesh, Sharma Swati, Gupta Ankur, Vijayvergiya Rajesh, Mehrotra Saurabh, Kumar Basant, Lad Deepesh, Patil Amol N, Shafiq Nusrat, Malhotra Samir

Abstract excerpt

OBJECTIVES: A study was conducted to develop and validate the warfarin pharmacogenetic dose optimization algorithm considering the clinical pharmacogenetic implementation consortium (CPIC) recommendations for the Asian ethnicity population. METHODS: The present prospective observational study recruited warfarin-receiving patients. We collected a three ml blood sample for VKORC1, CYP2C9*2, CYP2C9*3, and CYP4F2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aryl Hydrocarbon Hydroxylases

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PMID: 37075481
DOI: 10.1515/dmpt-2022-0189

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