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Pharmacogenomics of warfarin in populations of A frican descent

7 Jun 2012

Abstract excerpt

Warfarin is the most commonly prescribed oral anticoagulant worldwide despite its narrow therapeutic index and the notorious inter- and intra-individual variability in dose required for the target clinical effect. Pharmacogenetic polymorphisms are major determinants of warfarin pharmacokinetic and dynamics and included in several warfarin dosing algorithms. This review focuses on warfarin pharmacogenomics in...

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PMID: 22676711
DOI: 10.1111/j.1365-2125.2012.04354.x

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