Article
Variability in CYP2C9 allele frequency: a pilot study of its predicted impact on warfarin response among healthy South and North Indians.
Pharmacological reports : PR - 1 Jan 2013
Nahar Risha, Deb Roumi, Saxena Renu, Puri Ratna Dua, Verma Ishwar Chander
Abstract excerpt
BACKGROUND: Wide variability exists in the frequency of pharmacogeneticmarkers for anticoagulant response in different populations. There is insufficient data on the prevalence of these variant genotypes in the Indian population. This study aims to determine the frequency of various genotype combinations of CYP2C9*2, *3 and VKORC1-1639G>A polymorphisms in the South and North Indians. METHODS: Genotyping was...
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