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Article

Effect of CYP2C9 and VKORC1 genetic variations on warfarin dose requirements in Indian patients.

Pharmacological reports : PR - 1 Jan 2013

Natarajan Sripriya, Ponde Chandrashekhar K, Rajani Rajesh M, Jijina Farah, Gursahani Roopkumar, Dhairyawan Pradnya P, Ashavaid Tester F

Abstract excerpt

BACKGROUND: Warfarin, an oral anticoagulant is used in patients who are at increased risk of developing blood clots. The management of warfarin therapy is challenging because it shows large inter and intra individual variability in patient response due to factors like age, gender, diet, concurrent drug interactions and variations in CYP2C9 and VKORC1 genes. Studies implicate that polymorphisms in VKORC1 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24399734
DOI: 10.1016/s1734-1140(13)71496-8

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

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Effect of CYP2C9 and VKORC1 genetic variations on warfarin dose requirements in Indian patients.PMID 24399734Read ↗

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