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Article

Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene.

Respiratory medicine - 1 Oct 2014

Lee Jin Hwa, Cho Michael H, McDonald Merry-Lynn N, Hersh Craig P, Castaldi Peter J, Crapo James D, Wan Emily S, Dy Jennifer G, Chang Yale, Regan Elizabeth A, Hardin Megan, DeMeo Dawn L, Silverman Edwin K

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by marked phenotypic heterogeneity. Most previous studies have focused on COPD subjects with FEV1 < 80% predicted. We investigated the clinical and genetic heterogeneity in subjects with mild airflow limitation in spirometry grade 1 defined by the Global Initiative for chronic Obstructive Lung Disease (GOLD 1). METHODS: Data from current...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25154699
DOI: 10.1016/j.rmed.2014.07.018
PMCID: PMC4253548

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BICD1
CHRNA3
HHIP

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Source receipt: pubmed, retrieved 7 Sept 2026.

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