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Article

Regulation of fibroblast lipid storage and myofibroblast phenotypes during alveolar septation in mice.

American journal of physiology. Lung cellular and molecular physiology - 15 Oct 2014

McGowan Stephen E, McCoy Diann M

Abstract excerpt

Signaling through platelet-derived growth factor receptor-α (PDGFRα) is required for alveolar septation and participates in alveolar regeneration after pneumonectomy. In both adipose tissue and skeletal muscle, bipotent pdgfrα-expressing progenitors expressing delta-like ligand-1 or sex-determining region Y box 9 (Sox9) may differentiate into either lipid storage cells or myofibroblasts. We analyzed markers of...

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Source

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Identifiers

PMID: 25150063
DOI: 10.1152/ajplung.00144.2014
PMCID: PMC4200388

Genes

ACTA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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