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Article

Temporal, spatial, and phenotypical changes of PDGFRα expressing fibroblasts during late lung development.

Developmental biology - 15 May 2017

Endale Mehari, Ahlfeld Shawn, Bao Erik, Chen Xiaoting, Green Jenna, Bess Zach, Weirauch Matthew T, Xu Yan, Perl Anne Karina

Abstract excerpt

Many studies have investigated the source and role of epithelial progenitors during lung development; such information is limited for fibroblast populations and their complex role in the developing lung. In this study, we characterized the spatial location, mRNA expression and Immunophenotyping of PDGFRα+ fibroblasts during sacculation and alveolarization. Confocal microscopy identified spatial association of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28408205
DOI: 10.1016/j.ydbio.2017.03.020
PMCID: PMC5492510

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