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Article

Effects of COMT, DRD2, BDNF, and APOE Genotypic Variation on Treatment Efficacy and Cognitive Side Effects of Electroconvulsive Therapy.

The journal of ECT - 1 Jun 2015

Bousman Chad A, Katalinic Natalie, Martin Donel M, Smith Deidre J, Ingram Anna, Dowling Nathan, Ng Chee, Loo Colleen K

Abstract excerpt

OBJECTIVES: The aim of this study was to explore the main and interaction effects of the COMT Val158Met, DRD2 C957T, BDNF Val66Met, and APOE polymorphisms on treatment efficacy and cognitive side effects of electroconvulsive therapy (ECT). METHODS: A total of 117 adult inpatients with a diagnosis of major depressive disorder recruited from 3 hospitals were administered the Montgomery-Äsberg Depression Rating...

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Source

Identifiers

PMID: 25148110
DOI: 10.1097/YCT.0000000000000170

Genes

DRD2
BDNF
COMT
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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