Article
Genetics of Response to ECT, TMS, Ketamine and Esketamine.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2025
Franklin Clio E, Altinay Murat, Bailey Kala, Bhati Mahendra T, Carr Brent R, Conroy Susan K, Khurshid Khurshid, McDonald William M, Mickey Brian J, Murrough James W, Nestor Sean M, Nickl-Jockschat Thomas, Reti Irving M, Sanacora Gerard, Trapp Nicholas T, Viswanath Biju, Wright Jesse H, Zandi Peter P, Potash James B
Abstract excerpt
Treatment-resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined. Here, we review the current literature on the genetics of response to these treatment modalities. To date, the limited...
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