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Article

Influence of Val108/158Met COMT Gene Polymorphism on the Efficacy of Modified Electroconvulsive Therapy in Patients with Treatment Resistant Depression.

Cell biochemistry and biophysics - 1 Apr 2015

Lin Zhaoyu, He Hongbo, Zhang Chunping, Wang Zhijie, Jiang Miaoling, Li Qirong, Lan Xiaochang, Zhang Minling, Huang Xiong

Abstract excerpt

Depression is a common emotional disorder associated with increased risk of suicide and rate of disability. In this double-blinded control study, we tested the efficacy of modified electroconvulsive therapy (MECT) in patients with treatment resistant depression (TRD) using the Hamilton Depression Rating Scale for Depression (HAMD). The total scores of HAMD were found to be significantly decreased after the...

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Source

Identifiers

PMID: 25388840
DOI: 10.1007/s12013-014-0361-2

Genes

COMT
TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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