Article
Cellular adhesion gene SELP is associated with rheumatoid arthritis and displays differential allelic expression.
PloS one - 1 Jan 2014
Burkhardt Jana, Blume Mechthild, Petit-Teixeira Elisabeth, Hugo Teixeira Vitor, Steiner Anke, Quente Elfi, Wolfram Grit, Scholz Markus, Pierlot Céline, Migliorini Paola, Bombardieri Stefano, Balsa Alejandro, Westhovens René, Barrera Pilar, Radstake Timothy R D J, Alves Helena, Bardin Thomas, Prum Bernard, Emmrich Frank, Cornelis François, Ahnert Peter, Kirsten Holger
Abstract excerpt
In rheumatoid arthritis (RA), a key event is infiltration of inflammatory immune cells into the synovial lining, possibly aggravated by dysregulation of cellular adhesion molecules. Therefore, single nucleotide polymorphisms of 14 genes involved in cellular adhesion processes (CAST, ITGA4, ITGB1, ITGB2, PECAM1, PTEN, PTPN11, PTPRC, PXN, SELE, SELP, SRC, TYK2, and VCAM1) were analyzed for association with RA....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.