Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

mRNA expression analysis confirms CD44 splicing impairment in systemic lupus erythematosus patients.

Lupus - 1 Jun 2021

Latini Andrea, Novelli Lucia, Ceccarelli Fulvia, Barbati Cristiana, Perricone Carlo, De Benedittis Giada, Conti Fabrizio, Novelli Giuseppe, Ciccacci Cinzia, Borgiani Paola

Abstract excerpt

BACKGROUND: Systemic Lupus Erythematosus (SLE) is a complex chronic autoimmune disease characterized by several immunological alterations. T cells have a peculiar role in SLE pathogenesis, moving from the bloodstream to the peripheral tissues, causing organ damage. This process is possible for their increased adherence and migration capacity mediated by adhesion molecules, such as CD44. Ten different variant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Hyaluronan Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Lupus Erythematosus, Systemic

Share to Protein Isoforms

Share to RNA-Binding Proteins

Share to Severity of Illness Index

Share to T-Lymphocytes

Source

Identifiers

PMID: 33794704
DOI: 10.1177/09612033211004725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

mRNA expression analysis confirms CD44 splicing impairment in systemic lupus erythematosus patients.PMID 33794704Read ↗

Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity.Semantic proximity Read ↗

CD44 variant isoform expression in a variety of skin-associated autoimmune diseases.Semantic proximity Read ↗

Association study of rs1632947, rs1233334, and rs371194629 Polymorphisms in HLA-G Gene Expression and sHLA-G with lupusSemantic proximity Read ↗

STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.Semantic proximity Read ↗

Expression patterns of T cells-specific long noncoding RNAs in systemic lupus erythematosus patients carrying HLA risk/nonrisk alleles.Semantic proximity Read ↗

Estrogen‐Induced hsa‐miR‐10b‐5p Is Elevated in T Cells From Patients With Systemic Lupus Erythematosus and Down‐Regulates Serine/Arginine‐Rich Splicing Factor 1Semantic proximity Read ↗

Involvement of Multiple Variants of Soluble <scp>CD146</scp> in Systemic Sclerosis: Identification of a Novel Profibrotic FactorSemantic proximity Read ↗

CD44 splice variant involvement in the chronic inflammatory disease of the spinal cord: HAM/TSP.Semantic proximity Read ↗

Expression of S100A8 protein on B cells is associated with disease activity in patients with systemic lupus erythematosusSemantic proximity Read ↗

IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosusSemantic proximity Read ↗

CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?Semantic proximity Read ↗

The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.