Article
Bovine P-selectin mediates leukocyte adhesion and is highly polymorphic in dairy breeds.
Research in veterinary science - 1 Oct 2016
Chen Xing, Cheng Zhangrui, Werling Dirk, Pollott Geoffrey E, Salavati Mazdak, Johnson Kate F, Khan Faheem Ahmed, Wathes D Claire, Zhang Shujun
Abstract excerpt
Bovine P-selectin (SELP) mediates leukocyte rolling and primes leukocyte adhesion to endothelium, both essential for leukocyte recruitment to an infection site. We investigated SELP-mediated adhesion between bovine peripheral blood leukocytes (PBLs) and cultured bovine aortic endothelial cells pr...
Topics
- Animals
- Cattle
- Cell Adhesion
- Cell Movement
- Female
- Leukocytes
- P-Selectin
- Polymorphism, Single Nucleotide