Article
Integrating multi-omics for uncovering the architecture of cross-talking pathways in breast cancer.
PloS one - 1 Jan 2014
Wang Li, Xiao Yun, Ping Yanyan, Li Jing, Zhao Hongying, Li Feng, Hu Jing, Zhang Hongyi, Deng Yulan, Tian Jiawei, Li Xia
Abstract excerpt
Cross-talk among abnormal pathways widely occurs in human cancer and generally leads to insensitivity to cancer treatment. Moreover, alterations in the abnormal pathways are not limited to single molecular level. Therefore, we proposed a strategy that integrates a large number of biological sourc...
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