Article

talklr uncovers ligand-receptor mediated intercellular crosstalk

2020-02-02

Abstract excerpt

Single cell RNA-seq measures the transcriptomes of many cell types across diverse conditions. However, an emerging challenge is to uncover how different cell types communicate with each other to maintain tissue homeostasis, and how inter-cellular communications are perturbed in diseases. To address this problem, we developed talklr, an information theory-based approach to uncover potential ligand-receptor interact...

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Literature Corpus work: d719cf69-a002-5f7a-b06f-66aa84a24f00
DOI: 10.1101/2020.02.01.930602

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