Article
Construction and analysis of sample-specific driver modules for breast cancer.
BMC genomics - 20 Oct 2022
Chen Yuanyuan, Li Haitao, Sun Xiao
Abstract excerpt
BACKGROUND: It is important to understand the functional impact of somatic mutation and methylation aberration at an individual level to implement precision medicine. Recent studies have demonstrated that the perturbation of gene interaction networks can provide a fundamental link between genotype (or epigenotype) and phenotype. However, it is unclear how individual mutations affect the function of biological...
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