Article
Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer.
Oncotarget - 23 Aug 2016
Wei Runmin, De Vivo Immaculata, Huang Sijia, Zhu Xun, Risch Harvey, Moore Jason H, Yu Herbert, Garmire Lana X
Abstract excerpt
Endometrial Cancer (EC) is one of the most common female cancers. Genome-wide association studies (GWAS) have been investigated to identify genetic polymorphisms that are predictive of EC risks. Here we utilized a meta-dimensional integrative approach to seek genetically susceptible pathways that may be associated with tumorigenesis and progression of EC. We analyzed GWAS data obtained from Connecticut...
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