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Article

Subtype and regional regulation of prion biomarkers in sporadic C reutzfeldt– J akob disease

19 Aug 2014

Abstract excerpt

AIMS: Creutzfeldt-Jakob disease (CJD) is a rapid progressive neurological disease leading to dementia and death. Prion biomarkers are altered in the cerebrospinal fluid (CSF) of CJD patients, but the pathogenic mechanisms underlying these alterations are still unknown. The present study examined prion biomarker levels in the brain and CSF of sporadic CJD (sCJD) cases and their correlation with neuropathological...

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PMID: 25134744
DOI: 10.1111/nan.12175

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