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Profiles of 14-3-3 and Total Tau in CSF Samples of Chinese Patients of Different Genetic Prion Diseases

4 Sept 2019

Abstract excerpt

Background: The abnormal alterations of proteins 14-3-3 and tau in cerebrospinal fluid (CSF) are widely used for the diagnosis of sporadic Creutzfeldt-Jakob disease (sCJD), while the situations of CSF biomarkers in genetic prion diseases (gPrDs), particularly in Chinese gPrDs patients, have not been well documented. Methods: Here with the help of commercial 14-3-3 and total tau ELISA kits, we evaluated the levels...

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PMID: 31551692
DOI: 10.3389/fnins.2019.00934

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