Article
Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease.
Biomolecules - 12 Feb 2020
Llorens Franc, Villar-Piqué Anna, Hermann Peter, Schmitz Matthias, Calero Olga, Stehmann Christiane, Sarros Shannon, Moda Fabio, Ferrer Isidre, Poleggi Anna, Pocchiari Maurizio, Catania Marcella, Klotz Sigrid, O'Regan Carl, Brett Francesca, Heffernan Josephine, Ladogana Anna, Collins Steven J, Calero Miguel, Kovacs Gabor G, Zerr Inga
Abstract excerpt
Human prion diseases are classified into sporadic, genetic, and acquired forms. Within this last group, iatrogenic Creutzfeldt-Jakob disease (iCJD) is caused by human-to-human transmission through surgical and medical procedures. After reaching an incidence peak in the 1990s, it is believed that the iCJD historical period is probably coming to an end, thanks to lessons learnt from past infection sources that...
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