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Article

Evaluation of α‐synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases

18 Nov 2016

Abstract excerpt

INTRODUCTION: Accurate diagnosis of prion diseases and discrimination from alternative dementias gain importance in the clinical routine, but partial overlap in cerebrospinal fluid (CSF) biomarkers impedes absolute discrimination in the differential diagnostic context. METHODS: We established the clinical parameters for prion disease diagnosis for the quantification of CSF α-synuclein in patients with sporadic (n...

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PMID: 27870938
DOI: 10.1016/j.jalz.2016.09.013

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