Article
Cerebrospinal fluid markers in sporadic Creutzfeldt-Jakob disease.
International journal of molecular sciences - 1 Jan 2011
Zanusso Gianluigi, Fiorini Michele, Ferrari Sergio, Gajofatto Alberto, Cagnin Annachiara, Galassi Andrea, Richelli Silvia, Monaco Salvatore
Abstract excerpt
Sporadic Creutzfeldt-Jakob disease (sCJD) is the commonest form of human prion diseases, accounting for about 85% of all cases. Current criteria for intra vitam diagnosis include a distinct phenotype, periodic sharp and slow-wave complexes at electroencephalography (EEG), and a positive 14-3-3-protein assay in the cerebrospinal fluid (CSF). In sCJD, the disease phenotype may vary, depending upon the genotype at...
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