Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements.

The EMBO journal - 1 Sept 1997

D'Souza-Schorey C, Boshans R L, McDonough M, Stahl P D, Van Aelst L

Abstract excerpt

The ARF6 GTPase, the least conserved member of the ADP ribosylation factor (ARF) family, associates with the plasma membrane and intracellular endosome vesicles. Mutants of ARF6 defective in GTP binding and hydrolysis have a marked effect on endocytic trafficking and the gross morphology of the p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Carrier Proteins
Share to CHO Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cricetinae

Share to GTP-Binding Proteins

Share to Mutation

Share to Protein Binding

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 9312003
DOI: 10.1093/emboj/16.17.5445
PMCID: PMC1170175

Genes

ARF6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9312003-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements.PMID 9312003Read ↗

Separation of membrane trafficking and actin remodeling functions of ARF6 with an effector domain mutant.Semantic proximity Read ↗

Arf6 and its role in cytoskeletal modulation.Semantic proximity Read ↗

A novel GTPase-activating protein for ARF6 directly interacts with clathrin and regulates clathrin-dependent endocytosis.Semantic proximity Read ↗

ARF6 is required for growth factor- and rac-mediated membrane ruffling in macrophages at a stage distal to rac membrane targeting.Semantic proximity Read ↗

EFA6 facilitates the assembly of the tight junction by coordinating an Arf6-dependent and -independent pathway.Semantic proximity Read ↗

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.Semantic proximity Read ↗

Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments.Semantic proximity Read ↗

Arf family GTPases: roles in membrane traffic and microtubule dynamicsSemantic proximity Read ↗

Expression and properties of ADP-ribosylation factor (ARF6) in endocytic pathways.Semantic proximity Read ↗

Arf6 Regulates Endocytosis and Angiogenesis by Promoting Filamentous Actin AssemblySemantic proximity Read ↗

Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation.Semantic proximity Read ↗

Betacap73-ARF6 interactions modulate cell shape and motility after injury in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.