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Article

MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence.

Nature cell biology - 1 Mar 2004

Wada Teiji, Joza Nicholas, Cheng Hai-ying M, Sasaki Takehiko, Kozieradzki Ivona, Bachmaier Kurt, Katada Toshiaki, Schreiber Martin, Wagner Erwin F, Nishina Hiroshi, Penninger Josef M

Abstract excerpt

During the development of multicellular organisms, concerted actions of molecular signalling networks determine whether cells undergo proliferation, differentiation, death or ageing. Here we show that genetic inactivation of the stress signalling kinase, MKK7, a direct activator of JNKs in mice,...

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PMID: 15039780
DOI: 10.1038/ncb1098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15039780-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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