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Article

A cyanobacterial light activated adenylyl cyclase partially restores development of a Dictyostelium discoideum, adenylyl cyclase a null mutant.

Journal of biotechnology - 10 Dec 2014

Chen Zhi-Hui, Raffelberg Sarah, Losi Aba, Schaap Pauline, Gärtner Wolfgang

Abstract excerpt

A light-regulated adenylyl cyclase, mPAC, was previously identified from the cyanobacterium Microcoleus chthonoplastes PCC7420. MPAC consists of a flavin-based blue light-sensing LOV domain and a catalytic domain. In this work, we expressed mPAC in an adenylate cyclase A null mutant (aca-) of the eukaryote Dictyostelium discoideum and tested to what extent light activation of mPAC could restore the cAMP-dependent...

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Identifiers

PMID: 25128613
DOI: 10.1016/j.jbiotec.2014.08.008
PMCID: PMC4409636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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