Article
Marked anti-tumor effects of CD8(+)CD62L(+) T cells from melanoma-bearing mice.
Immunological investigations - 1 Jan 2015
Liao Yunmei, Geng Peiliang, Tian Yi, Miao Hongning, Liang Houjie, Zeng Rui, Ni Bing, Ruan Zhihua
Abstract excerpt
CD8(+)CD62L(+) T cells have been shown to play pivotal roles in anti-viral immunity, chronic myeloid leukemia and renal cell carcinoma. Recently, CD8(+)CD62L(+) T cells from naïve mice (nCD8(+)CD62L(+) T cells) have shown superior anti-tumor properties in melanoma-bearing mice. Considering that antigen-specific memory T cells have shown to possess more potent immunity than non-specific memory T cells, we...
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