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Article

Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapy.

Cancer immunology, immunotherapy : CII - 1 Feb 2011

Wölfl Matthias, Merker Katharina, Morbach Henner, Van Gool Stefaan W, Eyrich Matthias, Greenberg Philip D, Schlegel Paul G

Abstract excerpt

T cell-mediated immunotherapy against malignancies has been shown to be effective for certain types of cancer. However, ex vivo expansion of tumor-reactive T cells has been hindered by the low precursor frequency of such cells, often requiring multiple rounds of stimulation, resulting in full dif...

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Source

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Identifiers

PMID: 20972785
DOI: 10.1007/s00262-010-0928-8
PMCID: PMC3043230

Genes

CCR7
CD28

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20972785-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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