Article
Reassessment of CD62L as a marker of pre-effector T cells in the tumor draining lymph nodes of head and neck cancer patients.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Feb 2002
Strome Scott E, Martin Elizabeth, Flies Dallas, Khurana Dianne, Salomao Diva, Tamada Koji, Chapoval Andrei I, Kasperbauer Jan L, Olsen Kerry D, Chen Lieping
Abstract excerpt
OBJECTIVES: CD62L was evaluated as a determinant of human pre-effector T cells. STUDY DESIGN AND SETTING: Phenotype and cytokine secretion profiles of CD62L cells were determined based on activation status. RESULTS: CD62L(Low) T cells demonstrated significantly higher secretion of interleukin (IL)-10 and interferon (IFN)-gamma than did CD62L(High) T cells. After activation, the majority of cells expressed high...
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