Article
Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms.
Cancer research - 1 Jul 2013
Mao Yumeng, Poschke Isabel, Wennerberg Erik, Pico de Coaña Yago, Egyhazi Brage Suzanne, Schultz Inkeri, Hansson Johan, Masucci Giuseppe, Lundqvist Andreas, Kiessling Rolf
Abstract excerpt
Tumors can suppress the host immune system by employing a variety of cellular immune modulators, such as regulatory T cells, tumor-associated macrophages, and myeloid-derived suppressor cells (MDSC). In the peripheral blood of patients with advanced stage melanoma, there is an accumulation of CD1...
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