Article
Lymphocyte subpopulations in melanoma patients treated with dendritic cell vaccines.
Advances in experimental medicine and biology - 1 Jan 2007
Kadagidze Zaira G, Borunova Anna A, Zabotina Tatiana N
Abstract excerpt
The main goal of cancer immunotherapy is to induce or boost tumor-specific effector cells able to eliminate or reduce tumor progression. In this study, we characterized lymphocyte phenotypes in melanoma patients receiving dendritic cell (DC)-based vaccinotherapy. We found that several biological markers served as unfavorable prognostic factors for patients' response to therapy. This included decrease of CD4+ and...
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