Article
The prognostic impact of KRAS, its codon and amino acid specific mutations, on survival in resected stage I lung adenocarcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2014
Izar Benjamin, Zhou Haiyu, Heist Rebecca S, Azzoli Christopher G, Muzikansky Alona, Scribner Emily E F, Bernardo Lindsay A, Dias-Santagata Dora, Iafrate Anthony J, Lanuti Michael
Abstract excerpt
BACKGROUND: Despite complete surgical resection, patients with stage I non-small-cell lung cancer (NSCLC) are at risk for disease recurrence. The impact of common oncogenic driver mutations on prognosis in stage I NSCLC is limited. The pure prognostic value of KRAS mutational status was explored in resected stage I lung adenocarcinoma. METHODS: Mutation status was tested in patients who had complete resection of...
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