Article
KRAS mutation: should we test for it, and does it matter?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Mar 2013
Roberts Patrick J, Stinchcombe Thomas E
Abstract excerpt
Lung cancer is the leading cause of cancer mortality in the United States and worldwide. Previously, lung cancer was simplistically divided into non-small-cell lung cancer (NSCLC) and small-cell lung cancer. However, in the last decade, we have gone from a simplistic binary system of classifying lung cancer to defining NSCLC on the basis of molecular subsets. KRAS mutations represent the most common molecular...
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