Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma.

Cancer - 15 Jun 2013

Villaruz Liza C, Socinski Mark A, Cunningham Diana E, Chiosea Simion I, Burns Timothy F, Siegfried Jill M, Dacic Sanja

Abstract excerpt

BACKGROUND: The prognostic and therapeutic implications of the spectrum of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) oncogene substitutions in lung cancer remain poorly understood. The objective of this study was to determine whether KRAS oncogene substitutions differed with regard to prognosis or predictive value in lung adenocarcinoma. METHODS: KRAS oncogene substitutions and mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ras Proteins
Share to Adenocarcinoma
Share to Adenocarcinoma of Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Predictive Value of Tests

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Source

Open in PubMed Open full text

Identifiers

PMID: 23526491
DOI: 10.1002/cncr.28039
PMCID: PMC3674175

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma.PMID 23526491Read ↗

The prognostic impact of KRAS, its codon and amino acid specific mutations, on survival in resected stage I lung adenocarcinoma.Semantic proximity Read ↗

Prognostic value of specific KRAS mutations in lung adenocarcinomas.Semantic proximity Read ↗

Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy.Semantic proximity Read ↗

KRAS-G12C mutation is associated with poor outcome in surgically resected lung adenocarcinoma.Semantic proximity Read ↗

Prognostic and Predictive Value in KRAS in Non-Small-Cell Lung Cancer: A Review.Semantic proximity Read ↗

The prognostic value of Kirsten rat sarcoma viral oncogene homolog mutations in resected lung adenocarcinoma differs according to clinical features.Semantic proximity Read ↗

A Critical Review of the Prognostic and Predictive Implications of KRAS and STK11 Mutations and Co-Mutations in Metastatic Non-Small Lung CancerSemantic proximity Read ↗

Characterization of KRAS Mutation Subtypes in Non-small Cell Lung Cancer.Semantic proximity Read ↗

Prognostic impact of KRAS mutation subtypes in 677 patients with metastatic lung adenocarcinomas.Semantic proximity Read ↗

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.Semantic proximity Read ↗

KRAS mutations in lung cancer.Semantic proximity Read ↗

KRAS mutation: should we test for it, and does it matter?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.